UNESC Journal

EDITORIAL

Daniele Sabrina Cherubino Simões — 2025-07-21

INTERNATIONALIZATION OF HIGHER EDUCATION AT UNESC: EFFECTS OF A DECADE

Fernanda Araujo Gonzalez — 2025-07-21

The internationalization of Higher Education has been growing as a global strategy, expanding opportunities in the job market and promoting cultural diversity. This article analyzes the actions undertaken by the University Center of Espírito Santo (UNESC) to internationalize its education, focusing on institutional impacts and challenges faced. This is a descriptive, qualitative research based on documentary analysis of institutional records, public notices, internal reports, and data from the Center for Institutional and International Relations (NIU). Key developments include participation in the Science Without Borders program, the creation of the NIU, implementation of the English Tutorial, initiatives such as the Forest of Nations, international partnerships, virtual mobility through INILAT mov+, and the welcoming of international students in collaboration with the Unesc Sustainable Center (NUS) and São José Hospital (HSJ). Notable results include 67 students approved for virtual exchange programs, 25 selected peer mentors, and 87 inbound exchange students between 2013 and 2024. The findings suggest the importance of internationalization as a strategy to strengthen the institution's position in the global academic landscape and enrich students’ educational experience.

Keywords: Internationalization, UNESC, Virtual Mobility, Exchange, INILAT.

CO-INFECTION BY CANINE TRANSMISSIBLE VENEREAL TUMOR, HEPATOZOONOSIS, AND DIROFILARIASIS – A CLINICAL CHALLENGE IN DOGS – CASE REPORT

Breno Sérgio Corona Dias — 2025-07-21

O tumor venéreo transmissível canino (TVTC) é uma neoplasia de células redondas de origem mesenquimal, transmissível principalmente por coito, que afeta a mucosa genital de cães. Este estudo descreve um caso de coinfecção envolvendo TVTC, hepatozoonose canina e dirofilariose em um cão macho, sem raça definida, atendido na região metropolitana da Grande Vitória, Espírito Santo. O paciente apresentava sangramento peniano persistente e, após exames complementares, foi diagnosticado com TVTC por citologia aspirativa, hepatozoonose por esfregaço sanguíneo e dirofilariose através do teste SNAP 4Dx® Plus, que também revelou coinfecção por Ehrlichia canis e Anaplasma spp. O manejo terapêutico incluiu quimioterapia com sulfato de vincristina para o TVTC, dipropionato de imidocarb para hepatozoonose, doxiciclina para erliquiose e anaplasmose, e ivermectina para dirofilariose. O caso evidenciou o desafio clínico de tratar coinfecções em pacientes imunossuprimidos devido à quimioterapia, o que favorece a manifestação de infecções oportunistas como a hepatozoonose. A utilização de métodos diagnósticos complementares e o acompanhamento hematológico contínuo foram cruciais para o sucesso do tratamento. Este relato reforça a importância de uma abordagem clínica integrada para o diagnóstico e manejo de coinfecções, especialmente em regiões endêmicas para doenças transmitidas por vetores, visando otimizar o prognóstico e a qualidade de vida dos pacientes.

EPIDEMIOLOGICAL PROFILE AND TEMPORAL INCIDENCE OF REPORTS OF SUICIDE ATTEMPTS DUE TO EXOGENOUS POISONING IN TOWNS OF ESPÍRITO SANTO, 2007-2019

Gabriela Araújo dos Santos — 2025-07-22

Objective: To characterize the epidemiological profile and temporal incidence of reported suicide attempts by exogenous intoxication in Cachoeiro de Itapemirim, Colatina, Linhares, and Vitória from 2007 to 2019. Methods: A descriptive study based on data extracted from the Notifiable Diseases Information System, with time series analysis using the Joinpoint® regression program. Results: A total of 3,346 notifications were recorded in the towns analyzed, with a higher incidence among females (82.43%). A total of 1,690 cases involved individuals aged 20 to 39 years, accounting for 50.5% of all cases. White individuals were the most prevalent in Colatina, brown individuals in Linhares and Cachoeiro de Itapemirim, while Vitória had the highest proportion of cases with race recorded as unknown or not reported. Medications were, overwhelmingly, the most commonly used toxic agents (97.55%). Temporal analysis showed a significant variation in annual percentage change in Cachoeiro de Itapemirim, Colatina, and Linhares. Conclusion: The findings underscore the need for preventive strategies, especially regarding the use of medications in suicide attempts.

Keywords: Intoxication, Medications, Suicide, Epidemiological Surveillance.

COMPARISON OF VENTILATORY DISORDERS BETWEEN YOUNG-OLD AND OLDEST-OLD ADULTS: A CROSS-SECTIONAL STUDY BASED ON SPIROMETRY FINDINGS

Iara Silva Correia — 2025-07-22

Introduction: Elderly individuals can be set to youngest-old (from 60 to 79 years old) and oldest-old (more than 80 years old). Ventilatory disorders are among the respiratory dysfunctions that affect the elderly. As a manner of evaluating lung functions, spirometry is used: a non-invasive and low-cost exam. Objective: Compare types of ventilatory disorders and their prevalence among youngest-old and oldest-old elderlies. Material and Methods: This research is characterized as a cross-sectional, observational, analytical and retrospective epidemiological study. Data collection was conducted at a reference clinic for spirometry exams in the Alto Vale do Itajaí region, Santa Catarina, from January 2017 to December 2023. Exams of elderly patients were selected, and epidemiological and anthropometric data of the patients were observed, along with the results of spirometric findings and the classification of ventilatory disorders. Data analysis was performed using SPSS software and p<0.05 was considered statistically significant. Results: A total of 4,307 spirometry exams were analyzed, 87.1% of which were from the youngest-old and 12.9% from the oldest-old. Of these, 3,830 presented some type of disorder, with 88.1% in the youngest-old and 94.8% in the oldest-old. Restrictive disorders were the most prevalent (40.3%), affecting 1,736 patients. Mild disorders were more frequent in the youngest-old (35.3%) and severe disorders in the oldest-old (30.1%). Conclusion: Restrictive ventilatory disorders were the most prevalent in the entire population. The oldest-old had both a higher proportion of ventilatory disorders and greater severity.

Keywords: aging; respiratory tract diseases; respiratory function tests.

Drug interaction in breast cancer patients

Camila Carla dos Reis — 2025-07-22

Breast cancer is developed due to abnormal cell proliferation that turns it into a tumor with metastasis potential. This cancer occurs mainly in women, only 1% of breast cancer’s cases in Brazil is in men. Breast cancer is the main cause of women death in Brazil. The treatment for this cancer includes chemotherapy, hormonotherapy and/or targeted therapy, but it also includes others drugs to reduce side-effects as well as treating comorbidities. Thus, oncologic patients have a high risk of drug interaction and they need a multiprofessional team to ensure drug safety and efficiency. Therefore, this work aimed to analyze drugs interactions in breast cancer patients in use of antitumor drugs. A qualitative analysis was carried out by collecting data from medical records of patients with breast cancer treated at a philantroc hospital in Espírito Santo between the years 2012 and 2022. The main interactions identified were the association of doxorubicin with docetaxel or trastuzumab. Despite the large number of expected interactions, the number of team interventions was small, showing that the role of the pharmacist can be crucial for improving the quality of life of breast cancer patients.

INACTIVATION OF Staphylococcus aureus BY PHOTOBIOMODULATION WITH BLUE AND GREEN LIGHT

Leticia Aparecida Margotto Schneider — 2025-07-21

The emergence of antibiotic-resistant bacterial strains, such as methicillin-resistant Staphylococcus aureus (MRSA), has driven the search for alternative antimicrobial therapies. Light-based therapies have demonstrated bactericidal effects, which are influenced by factors such as wavelength, dosage, and bacterial density. This study aimed to develop a protocol for inactivating Staphylococcus aureus using blue and green light while preserving host cell integrity. The bactericidal effects of blue (465 nm) and green (525 nm) light were tested in vitro on Staphylococcus aureus (ATCC 29213) cultured for 24 hours and diluted to concentrations of 0.75 × 10⁸ CFU/mL and 0.375 × 10⁸ CFU/mL. Blue light at 60 J/cm² was applied three times within 24 hours, whereas green light at 100 J/cm² was applied once. Both wavelengths effectively reduced bacterial colonies, with the most significant reductions observed in the lower-density colonies (0.375 × 10⁸ CFU/mL), achieving a 95% reduction with blue light and 78% with green light. In higher-density colonies (0.75 × 10⁸ CFU/mL), blue light resulted in a 22% reduction, while green light produced a 47% reduction. Although complete eradication was not achieved, the significant reductions, particularly at lower bacterial densities, suggest that photobiomodulation with blue or green light, when used in combination with antibiotics, could be a promising strategy for reducing Staphylococcus aureus populations.

EVALUATION OF POISONING CASES BY HOUSEHOLD PRODUCTS IN ESPÍRITO SANTO

Izadora Correia dos Santos — 2025-07-22

Household cleaning products are destined for cleaning and disinfecting homes. However, these products can cause harm if incorrectly used, leading to mild or moderate intoxications. The COVID-19 pandemic further increased the use of household disinfectants in an effort to reduce or eliminate its transmission, resulting in cleaning products mixtures and excessive use of products without the necessary protection against intoxications. In this context, this study evaluated common forms of intoxication by sanitizing products, identifying risks characteristics of most affected people by these agents, in order to help academic community and health professionals to establish of Espírito Santo’s toxicological profile, contributing for a more adequate and effective care for intoxicated patients. Data collection was performed through a questionnaire. Most of the studied population is aware of household cleaning products risks and they have a high educational level. Although, they don't really know the signs and symptoms of intoxication and they do not take safety measures to avoid contamination.

ODONTOGENIC INFECTIONS AND CARDIORESPIRATORY COMPLICATIONS

Leandro de Oliveira Reckel — 2025-07-22

Odontogenic infections are common conditions in clinical dental practice, originating from inflammation of dental and periodontal tissues, with the potential to spread to adjacent structures and cause systemic infections. Among systemic complications, those affecting the cardiorespiratory system are particularly relevant, ranging from infective endocarditis to lung abscesses. The present study seeks to understand the relationship between these infections and systemic complications, especially those that affect the cardiovascular system and infections, contribute to the prevention, diagnosis and treatment of these conditions. A literature review was carried out in the Scielo, PubMed and Google Scholar databases to contribute to the process of systematizing and analyzing the results of other publications, with the aim of understanding the topic through independent studies. The results highlight a significant manifestation between odontogenic infections and complications in the cardiorespiratory system. Odontogenic infections are directly associated with cardiorespiratory complications, which reinforces the importance of a preventive approach and early diagnosis

NEGOTIATED OR PROTECTED JUSTICE? LIMITS OF SELF-COMPOSITION IN THE LABOR COURT OF COLATINA (ES)

Waléria Demoner Rossoni — 2025-07-21

The study examines self-composition, particularly conciliation, within the Labor Justice system as a tool for achieving social justice. It addresses the tension between those who advocate for expanding the parties’ autonomy in conflict resolution and those who reject such expansion under the strict lens of protection, grounded in the principled foundations of Labor Justice. The historical-normative approach outlines the origin of conciliation as an instrument aimed at social pacification, passing through the Consolidation of Labor Laws (CLT) and the Federal Constitution of 1988, emphasizing the importance of the former Labor Conciliation and Judgment Boards. In the second approach, the role of the labor judge is problematized in light of the imbalance between the parties, highlighting the importance of a proactive and critical posture during labor hearings. The study delves into an empirical analysis of the Labor Court of Colatina-ES, from 2020 to 2024, observing discrepancies between the increase in lawsuits and fluctuations in approved conciliatory practices, revealing structural and cultural limitations of self-composition. The third axis explores debates between the alternative justice model and labor law principles. Based on the public hearing held by the National Council of Justice (CNJ), it discusses pre-procedural mediation, the role of Judicial Centers for Conflict Resolution and Citizenship (CEJUSCS), and the potential risks of reducing worker protection. It concludes that a fair conciliatory policy requires a balance between autonomy and state protection, and that conciliation is only legitimate when aligned with fundamental rights and the social function of Labor Justice.

Keywords: Self-composition. Labor Justice. Social protection. Autonomy of will.